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Sorrento Announces Positive Phase IIa Study Results of Abivertinib for the Treatment of Relapsed/Refractory Marginal Zone Lymphoma (R/R MZL) and Its Plan for a Pivotal Phase III Study

Sorrento Therapeutics, Inc. has announced positive results from a phase IIa study of Abivertinib for the treatment of Relapsed/Refractory Marginal Zone Lymphoma (R/R MZL) in China. Abivertinib is a novel Bruton's tyrosine kinase (BTK) inhibitor that targets BTK irreversibly. The study included 27 R/R MZL patients treated with Abivertinib, and the overall response rate (ORR) was 59.3%, with 3 pat..

  • format_list_bulleted Pharmacology/BS
  • · 2023. 7. 6.
  • textsms

Propanc Biopharma Produces Synthetic Recombinant Proenzymes for Cancer Therapy Targeting Advanced Solid Tumors

Propanc Biopharma, Inc. announced the successful production of synthetic recombinant proenzymes trypsinogen and chymotrypsinogen through the Proenzyme Optimization Project 1 (POP1) joint research and drug discovery program. The project was conducted in collaboration with the Universities of Jaén and Granada, Spain. The synthetic development of these proenzymes aims to create a backup clinical co..

  • format_list_bulleted Pharmacology/BS
  • · 2023. 7. 6.
  • textsms

Kleine-Levin Syndrome Foundation Announces Updated Diagnostic Criteria for KLS

The Kleine-Levin Syndrome Foundation today announced updated diagnostic criteria for Kleine-Levin Syndrome (KLS) published in the International Classification of Sleep Disorders Third Edition (ICSD-3), the leading resource for diagnosing sleep disorders distributed by the American Academy of Sleep Medicine (AASM). The updated information about KLS in the ICSD-3 is based in large part on medical ..

  • format_list_bulleted Pharmacology/BS
  • · 2023. 7. 6.
  • textsms

Liberate Medical Secures $6.2M in Series B Financing

Liberate Medical Secures $6.2M in Series B Financing Series B Co-Led by a Large Strategic Investor and Scientific Health Development to Support the Pivotal Clinical Trial of the VentFree® Respiratory Muscle Stimulator CRESTWOOD, Ky.--(BUSINESS WIRE)-- Liberate Medical, an emerging leader in the development of novel non-invasive neurostimulation devices focused on transforming respiratory care, a..

  • format_list_bulleted Pharmacology/BS
  • · 2023. 7. 6.
  • textsms

Acasti Announces Alignment with FDA on GTX-104 Pivotal Phase 3 Safety Trial Protocol and Confirms Planned Initiation of STRIVE-ON in aSAH Patients in Calendar Q4 2023

Acasti Pharma Inc. has announced its alignment with the U.S. Food and Drug Administration (FDA) on the protocol for its pivotal Phase 3 trial of GTX-104, a novel injectable nimodipine formulation for intravenous infusion (IV), in patients hospitalized with aneurysmal subarachnoid hemorrhage (aSAH). The company also confirmed its planned initiation of the STRIVE-ON trial in aSAH patients in calen..

  • format_list_bulleted Pharmacology/BS
  • · 2023. 7. 6.
  • textsms

Ayala Pharmaceuticals Announces Successful End-of-Phase 2 Meeting with FDA Regarding AL102 for the Treatment of Desmoid Tumors

Ayala Pharmaceuticals, Inc. has successfully concluded an End-of-Phase 2 meeting with the FDA regarding AL102, a potential treatment for desmoid tumors. The company confirms agreement with the FDA on key elements of the Phase 3 segment of the ongoing RINGSIDE study, including the dosing regimen. Enrollment in Phase 3 is continuing as planned. Desmoid tumors are rare connective tissue tumors that..

  • format_list_bulleted Pharmacology/BS
  • · 2023. 7. 6.
  • textsms

F-star Announces Strategic Collaboration and Licence Agreement with Takeda to Develop Next-Generation Multi-Specific Antibodies

F-star Therapeutics, an invoX company, has announced a strategic collaboration and license agreement with Takeda to discover and develop next-generation multi-specific antibodies. The collaboration will focus on using F-star's proprietary platforms to research and develop immunotherapies for cancer patients. Under the agreement, F-star and Takeda will work together to research and develop novel ..

  • format_list_bulleted Pharmacology/BS
  • · 2023. 7. 6.
  • textsms

InnoCare Announces First Psoriasis Patient Dosed in Clinical Trial of TYK2 Allosteric Inhibitor ICP-488 in China

InnoCare Pharma (HKEX: 09969; SSE: 688428) has announced that the first psoriasis patient has been dosed in a clinical trial of their TYK2 allosteric inhibitor ICP-488 in China. The phase I clinical trial has already completed single ascending doses (SAD) and multiple ascending doses (MAD) of ICP-488, showing a well-tolerated safety profile. The ongoing study aims to evaluate the safety and effi..

  • format_list_bulleted Pharmacology/BS
  • · 2023. 7. 6.
  • textsms

Daxor Corporation Awarded $1.1 Million Contract from the United States Defense Health Agency for Added Capabilities to its Point-of-Care Blood Volume Analyzer

Daxor Corporation, the global leader in blood volume measurement technology, has been awarded a $1.1 million contract from the United States Defense Health Agency (DHA) to add electronic medical record (EMR) integration capabilities to its blood volume analyzer. This marks the fifth Small Business Innovative Research (SBIR) contract awarded to Daxor for their next generation technologies. The in..

  • format_list_bulleted Pharmacology/BS
  • · 2023. 7. 6.
  • textsms

Simufilam Slowed Cognitive Decline in a Randomized Withdrawal Trial of Mild-to-Moderate Alzheimer’s Disease

  • format_list_bulleted Pharmacology/BS
  • · 2023. 7. 6.
  • textsms
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